Hormone Pellet Therapy


Restoration of hormone balance utilizing physiologic doses of biologically identical hormones can be safely accomplished in a variety of different ways. Under the guidance of Dr. Edwards, patients can choose compounded hormone combinations in topical, oral, sublingual, or vaginal form. Dr. Edwards will provide individual treatment recommendations based upon what is optimal and safe for each patient.

For patients who are stabilized on their current hormone regimen or for those in whom other dosing methods are is ineffective or inconvenient, bio-identical hormones (specifically estrogen and testosterone) can be administered in pellet form.


Pellets are very small, cylindrically shaped hormone composites that have been tightly pressed together. Approximately three hormone pellets could fit onto the face of a dime. Soy and/or yam plants are typically the source of bio-identical hormones regardless of the mode of administration. Most hormone pellets are made by compounding pharmacists and delivered in sterile glass containers.


After placement, pellets deliver consistent and physiologic levels of hormones for up to five months depending upon the patient. Pellets may more closely mimic optimal physiologic hormone action by providing consistent hormone levels rather than drastic fluctuations sometimes encountered with other forms of hormone replacement. Neither pellets nor topically administered compounded bio-identical hormones increase the risk of blood clots like conventional or synthetic hormone replacement therapy.


The hormonal effects of pellets typically last between three to four months in women and four to five months in men. Since the pellets dissolve on their own over time, there is no need to remove them before replacing them. Pellets need to be replaced approximately two to four times per year depending upon the patient, their lifestyle, and their rate of hormone metabolism. Dr. Edwards closely monitors all patients on any form of bio-identical hormone replacement and conducts appropriate hormone testing at regular intervals.

Insurance companies typically do not reimburse for pellet implant insertion, and the cost varies depending upon the patient, the amount of hormone needed, and the number of pellet placements required. The pellets themselves typically cost the patient $30 to $40 depending upon the compounding pharmacy used.